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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1196208Generated: November 2, 2026

(3S,4S)-4-(1-hydroxymethylethenyl)-3-(1-(R)-benzyloxycarbonyloxyethyl)-2-azetidinone → (3S,4S)-4-(1-tetrahydropyranyloxymethylethenyl)-3-(1-(R)-benzyloxycarbonyloxyethyl)-2-azetidinone

https://huagongshe.com/reaction/1196208

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(3S,4S)-4-(1-hydroxymethylethenyl)-3-(1-(R)-benzyloxycarbonyloxyethyl)-2-azetidinoneHCID 15000240—
Reactant(3S,4S)-4-(1-tetrahydropyranyloxymethylethenyl)-3-(1-(R)-benzyloxycarbonyloxyethyl)-1-tetrahydropyranyl-2-azetidinoneHCID 15000245—
Product(3S,4S)-4-(1-tetrahydropyranyloxymethylethenyl)-3-(1-(R)-benzyloxycarbonyloxyethyl)-2-azetidinoneHCID 15000244—

Reaction Steps

Following the procedure as described in Example 15-(1) but replacing the starting material by (3S,4S)-4-(1-hydroxymethylethenyl)-3-(1-(R)-benzyloxycarbonyloxyethyl)-2-azetidinone, (3S,4S)-4-(1-tetrahydropyranyloxymethylethenyl)-3-(1-(R)-benzyloxycarbonyloxyethyl)-1-tetrahydropyranyl-2-azetidinone (Compound A) and (3S,4S)-4-(1-tetrahydropyranyloxymethylethenyl)-3-(1-(R)-benzyloxycarbonyloxyethyl)-2-azetidinone (Compound B) were obtained.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05112966
Source datasetuspto-grants-1992_05
ORD IDord-0e21690334f74b1e91484789ad4a163a
Source noteuspto-grants-1992_05