HCID 22841886, compound → HCID 22841888, compound

Participants

Reaction Steps

A solution of (3S,4S)-4-(1-ethoxycarbonylethenyl)-3-(1-(R)-benzyloxycarbonyloxyethyl)-2-azetidinone (40.0 g) in ethanol (600 ml) was hydrogenated under hydrogen atmosphere in the presence of 10% Pd/C (20.0 g) at room temperature for 3 hours. The mixture was filtered, and the filtrate was evaporated in vacuo to give (3S,4S)-4-(1-ethoxycarbonylethyl)-3-(1-(R)-hydroxyethyl)-2-azetidinone as a yellowish oil.

Provenance & Evidence