HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Methylmorpholine → HCID 178512173, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Methylmorpholine | HCID 7972 | — |
| Reactant | 1,2-Pyrrolidinedicarboxylic acid, 2-(2,5-dioxo-1-pyrrolidinyl) 1-(phenylmethyl) ester, (2S)- | HCID 853482 | — |
| Reactant | Hydrogen chloride-ethyl acetate | HCID 21866389 | — |
| Reactant | HCID 178454227 | HCID 178454227 | — |
| Solvent | Diethyl Ether | HCID 3283 | — |
| Product | HCID 178512173 | HCID 178512173 | — |
Reaction Steps
The desired compound was prepared from 4.0 g of Boc-Ser(Bzl)-Pro-Arg(NO2)-OBzl, 20 ml of 4N HCl-AcOEt, 1 ml of NMM and 2.2 g of Z-Pro-OSu in the same manner as in Example 26-(4). The ether treatment was performed to obtain the desired compound as a crystalline product.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05112947 |
| Source dataset | uspto-grants-1992_05 |
| ORD ID | ord-914bc4c877c04e98996da2e7444f7574 |
| Source note | uspto-grants-1992_05 |