HuagongsheHuagongshe Chemistry Print Report · For research reference only
20-(5,5-Dimethyl-1,3-dioxan-2-yl)pregna-1,4,6-trien-3-one → 1alpha,2alpha-Epoxy-3-oxopregna-4,6-diene-20-carbaldehyde
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 20-(5,5-Dimethyl-1,3-dioxan-2-yl)pregna-1,4,6-trien-3-one | HCID 22843932 | — |
| Reactant | 20-(5,5-Dimethyl-1,3-dioxan-2-yl)-1alpha,2alpha-epoxypregna-4,6-dien-3-one | HCID 86745797 | — |
| Product | 1alpha,2alpha-Epoxy-3-oxopregna-4,6-diene-20-carbaldehyde | HCID 22843883 | 60.2% |
Reaction Steps
The procedure of Example 26 was repeated except that 0.426 g (1.0 mmole) of 20-(5,5-dimethyl-1,3-dioxan-2-yl)-1α,2α-epoxypregna-4,6-dien-3-one was used in lieu of 0.410 g of 20-(5,5-dimethyl-1,3-dioxan-2-yl)pregna-1,4,6-trien-3-one to give 0.205 g of 1α, 2α-epoxy-3-oxopregna-4,6-diene-20-carbaldehyde (yield: 60%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05112998 |
| Source dataset | uspto-grants-1992_05 |
| ORD ID | ord-3e0995e51c9a40bd8de8722993a1d4cf |
| Source note | uspto-grants-1992_05 |