HuagongsheHuagongshe Chemistry Print Report · For research reference only
20-(5,5-Dimethyl-1,3-dioxan-2-yl)-1alpha, 2alpha-epoxypregna-5,7-dien-3beta-yl acetate → 20-(1,3-Dioxolan-2-yl)-1alpha,2alpha-epoxypregna-5,7-dien-3beta-ol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 20-(5,5-Dimethyl-1,3-dioxan-2-yl)-1alpha, 2alpha-epoxypregna-5,7-dien-3beta-yl acetate | HCID 86745805 | — |
| Reactant | 20-(1,3-Dioxolan-2-yl)--epoxypregna-5,7-dien-3beta-yl acetate | HCID 86745820 | — |
| Product | 20-(1,3-Dioxolan-2-yl)-1alpha,2alpha-epoxypregna-5,7-dien-3beta-ol | HCID 86745819 | 90.1% |
Reaction Steps
The procedure of Example 23 was repeated except that 4.5 mg (0.0106 mmole) of 20-(1,3-dioxolan-2-yl)--epoxypregna-5,7-dien-3β-yl acetate was used in lieu of 5 mg of 20-(5,5-dimethyl-1,3-dioxan-2-yl)-1α,2α-epoxypregna-5,7-dien-3β-yl acetate to give 3.7 mg of 20-(1,3-dioxolan-2-yl)-1α,2α-epoxypregna-5,7-dien-3β-ol (yield: 90%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05112998 |
| Source dataset | uspto-grants-1992_05 |
| ORD ID | ord-b7b16da6c075435f9fa37a6d2691746e |
| Source note | uspto-grants-1992_05 |