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HRID1196363

反应详情

EQUATION

反应方程式

HRID 1196363 的结构方程式

REACTANTS

反应物

2
反应SMILES：CC(C1OCC(C)(C)CO1)[C@H]1CC[C@H]2[C@@H]3C=C[C@@]4(O)C[C@@H](O[Si](C)(C)C(C)(C)C)C[C@H](O)[C@]4(C)[C@H]3CC[C@]12C
HCID67852928

未命名化合物

反应SMILES：CC(C1OCCO1)[C@H]1CC[C@H]2[C@@H]3C=C[C@@]4(O)C[C@@H](O)C[C@H](O)[C@]4(C)[C@H]3CC[C@]12C
HCID67852995

未命名化合物

PRODUCTS

产物

1
反应SMILES：COCO[C@H]1C[C@H](O[Si](C)(C)C(C)(C)C)C[C@]2(O)C=C[C@H]3[C@@H]4CC[C@H](C(C)C5OCC(C)(C)CO5)[C@@]4(C)CC[C@@H]3[C@@]12C
HCID67852946

未命名化合物

收率 74.2%

PROCEDURE

实验过程

The reaction and workup procedures of Example 110 were repeated except that 400 mg of 20-(5,5-dimethyl-1,3-dioxan-2-yl)-3β-(tert-butyldimethylsilyl)oxypregn-6-ene-1α,5α-diol was used in lieu of 400 mg of 20-(1,3-dioxolan-2-yl)pregn-6-ene-1α,3β,5α-triol to give 320 mg of 20-(5,5-dimethyl-1,3-dioxan-2-yl)-3β-(tertbutyldimethylsilyl)oxy-1α-(methoxymethyl)oxypregn-6-en-5α-ol showing the following physical properties.

WORKUP

后处理

  1. customThe reaction and workup procedures of Example 110