huagongshe.com
HRID1196379

反应详情

EQUATION

反应方程式

HRID 1196379 的结构方程式

REACTANTS

反应物

2
结构：COC(=O)O[C@@H]1CC2=C[C@@H](OC(=O)OC)[C@H]3[C@@H]4CC[C@H](C(C)C5OCC(C)(C)CO5)[C@@]4(C)CC[C@@H]3[C@@]2(C)[C@@H](OC(=O)OC)C1
HCID57141858

未命名化合物

结构：CNC(=O)O[C@H]1C[C@H](OC(=O)c2ccccc2)CC2=C[C@@H](OC(=O)OC)[C@H]3[C@@H]4CC[C@H](C(C)C(OC)OC)[C@@]4(C)CC[C@@H]3[C@]21C
HCID67852955

未命名化合物

PRODUCTS

生成物

1
结构：COC(OC)C(C)[C@H]1CC[C@H]2[C@@H]3[C@H](O)C=C4C[C@@H](O)C[C@H](O)[C@]4(C)[C@H]3CC[C@]12C
HCID67852991

未命名化合物

收率 81.3%

PROCEDURE

实验过程

The reaction and workup procedures of Example 140 were repeated except that 85 mg of 3β-benzoyloxy-21,21-dimethoxy-20-methyl-1α-(N-methylcarbamoyl)oxy-7α-(methoxycarbonyl)oxypregn-5-ene was used in lieu of 100 mg of 20-(5,5-dimethyl-1,3-dioxan-2-yl)-1α,3β,7α-tris(methoxycarbonyloxy)pregn-5-ene to give 45 mg of 21,21-dimethoxy-20-methylpregn-5-ene-1α,3β,7α-triol showing the following physical properties.

WORKUP

后处理

  1. customThe reaction and workup procedures of Example 140