HuagongsheHuagongshe Chemistry Print Report · For research reference only
1alpha,3beta-Bis(methoxycarbonyloxy)pregna-5,7-diene-20-carbaldehyde → 20-(1,3-Dioxolan-2-yl)-3beta-(methoxymethyl)oxypregna-5,7-dien-1alpha-ol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1alpha,3beta-Bis(methoxycarbonyloxy)pregna-5,7-diene-20-carbaldehyde | HCID 54367523 | — |
| Reactant | 20-(1,3-Dioxolan-2-yl)-1alpha-acetoxy-3beta-(methoxymethyl)oxypregna-5,7-diene | HCID 67852943 | — |
| Product | 20-(1,3-Dioxolan-2-yl)-3beta-(methoxymethyl)oxypregna-5,7-dien-1alpha-ol | HCID 67852889 | 79% |
Reaction Steps
The reaction and workup procedures of Example 164 were repeated except that 100 mg of 20-(1,3-dioxolan-2-yl)-1α-acetoxy-3β-(methoxymethyl)oxypregna-5,7-diene was used in lieu of 100 mg of 1α,3β-bis(methoxycarbonyloxy)pregna-5,7-diene-20-carbaldehyde to give 72 mg of 20-(1,3-dioxolan-2-yl)-3β-(methoxymethyl)oxypregna-5,7-dien-1α-ol showing the following physical properties.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05112998 |
| Source dataset | uspto-grants-1992_05 |
| ORD ID | ord-e30c7e99cb3d4f5895f4f05644502a27 |
| Source note | uspto-grants-1992_05 |