HuagongsheHuagongshe Chemistry Print Report · For research reference only
21,21-Dimethoxy-20-methylpregna-5,7-diene-1alpha,3betadiol → 1alpha,3beta-Dihydroxypregna-5,7-diene-20-carbaldehyde
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 21,21-Dimethoxy-20-methylpregna-5,7-diene-1alpha,3betadiol | HCID 57189343 | — |
| Reactant | 20-(5,5-Dimethyl-1,3-dioxan-2-yl)-1alpha,3beta-bis(methoxycarbonyloxy)pregn-5,7-diene | HCID 67852971 | — |
| Product | 1alpha,3beta-Dihydroxypregna-5,7-diene-20-carbaldehyde | HCID 53892781 | 51% |
Reaction Steps
The reaction and workup procedures of Example 156 were repeated except that 100 mg of 21,21-dimethoxy-20-methyl-pregna-5,7-diene-1α,3β-diol was used in lieu of 100 mg of 20-(5,5-dimethyl-1,3-dioxan-2-yl)-1α,3β-bis(methoxycarbonyloxy)pregna-5,7-diene to give 45 mg of 1α,3β-dihydroxypregna-5,7-diene-20-carbaldehyde showing the following physical properties.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05112998 |
| Source dataset | uspto-grants-1992_05 |
| ORD ID | ord-d36633b7ae97462f8e4a543c64412826 |
| Source note | uspto-grants-1992_05 |