Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Ethyl bromoacetate → HCID 21671609, 화합물
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Ethyl bromoacetate | HCID 7748 | — |
| 반응물 | 3-Butylcyclohex-2-en-1-one | HCID 239095 | — |
| 반응물 | Lithium diisopropylamide | HCID 2724682 | — |
| 반응물 | 6-(Carbethoxymethyl)-3-methyl-2-cyclohexen-1-one | HCID 21671608 | — |
| 용매 | Tetrahydrofuran | HCID 8028 | — |
| 생성물 | HCID 21671609 | HCID 21671609 | 83.5% |
반응 단계
The reaction of 3-n-butyl-2-cyclohexen-1-one (3.0 g, 19.7 mmoles) in 10 ml of THF with lithium diisopropylamide (2.17 mmoles) followed by ethyl bromoacetate (3.96 g, 23.6 mmoles) in 10 ml of THF, at -78° C. under argon, was conducted in a similar manner to the synthesis of 6-(carbethoxymethyl)-3-methyl-2-cyclohexen-1-one described in Example II, and a yield of 3.92 g (83%) of 6-(carbethoxymethyl)-3-n-butyl-2-cyclohexen-1-one was obtained.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05114493 |
| 출처 데이터셋 | uspto-grants-1992_05 |
| ORD ID | ord-b392d21db49140da94f5a98682872e59 |
| 출처 메모 | uspto-grants-1992_05 |