HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Methylbenzaldehyde → (4-Methylphenyl)[4-(trimethylsilyl)phenyl]methanone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Methylbenzaldehyde | HCID 7725 | — |
| Reactant | (p-Chlorophenyl)trmethylsilane | HCID 66351 | — |
| Reactant | Magnesium | HCID 5462224 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | (4-Methylphenyl)[4-(trimethylsilyl)phenyl]methanone | HCID 19898435 | — |
Reaction Steps
C-1) A Gringnard reagent consisting of 0.2 mol of 4-trimethylsilylchlorobenzene and 0.2 mol of magnesium was prepared in tetrahydrofuran, mixed with 0.2 mol of 4-methylbenzaldehyde and subjected to Oppenauer oxidation reaction to obtain 4-methyl-4'-trimethylsilylbenzophenone represented by the following chemical structural formula: ##STR19## The reaction product was actually used in the form of a 15% solution in isopropyl alcohol.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05114794 |
| Source dataset | uspto-grants-1992_05 |
| ORD ID | ord-22beaf8e108342aab037e60817c1e6ed |
| Source note | uspto-grants-1992_05 |