HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethyl bromodifluoroacetate → 4-Benzyloxycarbonylamino-5-cyclohexyl-2,2-difluoro-3-hydroxypentanoic acid, ethyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethyl bromodifluoroacetate | HCID 69585 | — |
| Reactant | N-benzyloxycarbonyl-3-cyclohexylalaninal | HCID 10869979 | — |
| Catalyst | Zinc | HCID 23994 | — |
| Product | 4-Benzyloxycarbonylamino-5-cyclohexyl-2,2-difluoro-3-hydroxypentanoic acid, ethyl ester | HCID 14142082 | 37% |
Reaction Steps
The title compound was prepared in 37% yield from N-benzyloxycarbonyl-3-cyclohexylalaninal, ethyl bromodifluoroacetate and zinc by the procedure described in Example 1.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05114927 |
| Source dataset | uspto-grants-1992_05 |
| ORD ID | ord-18c6cc9b63e845c78bbe7780bd05481b |
| Source note | uspto-grants-1992_05 |