Hydrochloric Acid → HCID 19898957, compound

Participants

Reaction Steps

A solution of 2-(2H-phthalazin-1-on-2-yl)-N-methyl-N-benzylethylamine (41.5 g) in ethanol (1000 ml) and concentrated hydrochloric acid (50 ml) containing 5% palladium on charcoal (4.1 g) was stirred under a hydrogen atmosphere (50 p.s.i.) at room temperature for 18 hours. The reaction mixture was filtered and evaporated to afford a solid which was recrystallised from isopropanol to afford the title compound, yield 22.5 g, m.p. 200°-201°.

Provenance & Evidence