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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1196552Generated: October 27, 2026

Triethyl 4-phosphonocrotonate, mixture of isomers → (2E,4E)-N-Isobutyl 12-(6-trifluoromethyl-2-quinolinyloxy) dodeca-2,4-dienamide

https://huagongshe.com/reaction/1196552

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTriethyl 4-phosphonocrotonate, mixture of isomersHCID 5365783—
Reactant2-Chloro-6-(trifluoromethyl)quinolineHCID 10911411—
Product(2E,4E)-N-Isobutyl 12-(6-trifluoromethyl-2-quinolinyloxy) dodeca-2,4-dienamideHCID 23172662—

Reaction Steps

Starting from 2-chloro-6-trifluoromethylquinoline (prepared as for Compound 23 starting from 4-trifluoromethyl aniline (ex. Aldrich)), and using triethyl 4-phosphonocrotonate.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05114940
Source datasetuspto-grants-1992_05
ORD IDord-99352605a4a04fa08bc677ca164bbf7b
Source noteuspto-grants-1992_05