Methyl iodide → HCID 19898683, compound

Participants

Reaction Steps

10-(2-Quinolinyloxy)decan-1-al (3.5 g) in dry diethyl ether (15 ml was treated with methyl magnesium iodide in dry ether (2 ml) prepared from magnesium (0.29 g) and iodomethane (0.75 ml). After quenching with satd. aqueous ammonium chloride the reaction was worked-up in the usual manner and the crude product purified by column chromatography on silica (8:2, hexane:ether) to give 11-(2-quinolinyloxy)undecan-2-ol (1.24 g).

Provenance & Evidence