反应详情

To a mixture of 2-(cyclohexylmethyl)indene (2.0 g, 9.4 mmol) in 40 mL of hexanes were added 6.0 mL of butyl lithium (1.6 M hexane; 9.6 mmol). The mixture was stirred overnight, the mother liquor decanted and the solid dissolved in THF. To this was added N-(1,1-dimethylethyl)dimethylsilanamine chloride (1.64 g, 9.9 mmol) and the solution stirred for 1 hour. The volatiles were removed in vacuo, the residue extracted with hexane, filtered and the volatiles removed in vacuo to give 2.85 g (90 percent) of a yellow oil.

1. customthe mother liquor decanted
2. dissolutionthe solid dissolved in THF
3. stirringthe solution stirred for 1 hour
4. customThe volatiles were removed in vacuo
5. extractionthe residue extracted with hexane
6. filtrationfiltered
7. customthe volatiles removed in vacuo