HuagongsheHuagongshe Chemistry Print Report · For research reference only
p-Toluenesulfonic acid → beta-Chloralose
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | p-Toluenesulfonic acid | HCID 6101 | — |
| Reactant | Chloroform | HCID 6212 | — |
| Reactant | (2R,3S,4R,5R)-2,3,4,5,6-pentahydroxyhexanal | HCID 107526 | — |
| Product | beta-Chloralose | HCID 5284343 | — |
Reaction Steps
Under stirring 0.05 g of 4-methyl-benzene sulphonic acid and 20 ml of chloroform are added to a mixture of 4.5 g of glucose and 19 g of choral. The mixture is heated to reflux temperature and the formed water is separated by means of a Dean-Stark apparatus. The solvent is distilled off, then the mixture is kept at a temperature of 60° C. for 20 minutes. The separated material is filtered off.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05116402 |
| Source dataset | uspto-grants-1992_05 |
| ORD ID | ord-d53c1fbb33c249efbc3cc08fedce34e7 |
| Source note | uspto-grants-1992_05 |