Methyl iodide → HCID 18956533, compound

HRID 1196935Notes

Reaction equation

[F:1][C:2]1[CH:7]=[C:6]([F:8])[CH:5]=[CH:4][C:3]=1[C:9](=[O:17])[CH2:10][C:11]1[N:16]=[CH:15][CH:14]=[CH:13][N:12]=1.I[CH3:19]>>[F:1][C:2]1[CH:7]=[C:6]([F:8])[CH:5]=[CH:4][C:3]=1[C:9](=[O:17])[CH:10]([C:11]1[N:12]=[CH:13][CH:14]=[CH:15][N:16]=1)[CH3:19]

Participants

Reactant 2

HCID 6328Methyl iodide

HCID 18956534HCID 18956534, compound

Product 1

HCID 18956533HCID 18956533, compoundYield 89%

Procedure

Methylation of the product of part (i) (3.50 g) with iodomethane (5.32 g) according to the method of Example 11(ii) gave the title compound (3.30 g), m.p. 118°-119°.

Sources & evidence

ORD record: ord-4a27ed891a344f09a6bde9387909343f
Source dataset: uspto-grants-1992_05
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05116844

Reaction notes

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