HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethyl Acetate → HCID 18956531, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethyl Acetate | HCID 8857 | — |
| Reactant | 1H-1,2,4-Triazole | HCID 9257 | — |
| Reactant | Sodium | HCID 5360545 | — |
| Reactant | HCID 18956528 | HCID 18956528 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 18956531 | HCID 18956531 | — |
Reaction Steps
Treatment of the product of part (iii) (0.80 g) with 1H-1,2,4-triazole, sodium salt (0.82 g) in N,N-dimethylformamide according to the method of Example 12(iv), followed by chromatography of the crude product on silica gel using ethyl acetate as eluant, first gave, after combination and evaporation of appropriate fractions, the title compound, diastereoisomeric pair A, (0.26 g), m.p. 193°-195° (from dichloromethane/ether).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05116844 |
| Source dataset | uspto-grants-1992_05 |
| ORD ID | ord-a36ffca0ef1c424f81358b7d3caf0ed9 |
| Source note | uspto-grants-1992_05 |