HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 18956504, compound → HCID 18956546, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 18956504 | HCID 18956504 | — |
| Catalyst | Potassium Hydroxide | HCID 14797 | — |
| Solvent | Isopropanol | HCID 3776 | — |
| Product | HCID 18956546 | HCID 18956546 | 84.6% |
Reaction Steps
A solution of the product of Example 21 (70 mg) in isopropanol (4 ml) containing 50% aqueous potassium hydroxide (4 drops) was heated under reflux for 4 hours and then evaporated. Water was added to the residue and the mixture was extracted several times with ethyl acetate. The combined organic extracts were washed with water and dried (MgSO4). Evaporation of the solvent gave the title compound as an amorphous foam, (49 mg).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05116844 |
| Source dataset | uspto-grants-1992_05 |
| ORD ID | ord-1a32542180dd43ffa4caa0be00f1df0d |
| Source note | uspto-grants-1992_05 |