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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1196952Generated: October 30, 2026

HCID 18956504, compound → HCID 18956546, compound

https://huagongshe.com/reaction/1196952

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 18956504HCID 18956504—
CatalystPotassium HydroxideHCID 14797—
SolventIsopropanolHCID 3776—
ProductHCID 18956546HCID 1895654684.6%

Reaction Steps

A solution of the product of Example 21 (70 mg) in isopropanol (4 ml) containing 50% aqueous potassium hydroxide (4 drops) was heated under reflux for 4 hours and then evaporated. Water was added to the residue and the mixture was extracted several times with ethyl acetate. The combined organic extracts were washed with water and dried (MgSO4). Evaporation of the solvent gave the title compound as an amorphous foam, (49 mg).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05116844
Source datasetuspto-grants-1992_05
ORD IDord-1a32542180dd43ffa4caa0be00f1df0d
Source noteuspto-grants-1992_05