Sodium borohydride → HCID 131717405, compound

HRID 1196960Notes

Reaction equation

HRID 1196960 reaction equation
[ClH:1].[CH3:2][N:3]([CH3:31])[CH2:4][CH2:5][N:6]([C:17]1[CH:22]=[CH:21][CH:20]=[CH:19][C:18]=1[S:23][CH2:24][C:25]1[CH:30]=[CH:29][CH:28]=[CH:27][CH:26]=1)[C:7](=[O:16])[C:8](=[O:15])[C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=1.[BH4-].[Na+]>CO>[ClH:1].[CH3:2][N:3]([CH3:31])[CH2:4][CH2:5][N:6]([C:17]1[CH:22]=[CH:21][CH:20]=[CH:19][C:18]=1[S:23][CH2:24][C:25]1[CH:30]=[CH:29][CH:28]=[CH:27][CH:26]=1)[C:7](=[O:16])[CH:8]([OH:15])[C:9]1[CH:10]=[CH:11][CH:12]=[CH:13][CH:14]=1

Participants

4

Reactant 2

HCID 4311764Sodium borohydrideHCID 131717406HCID 131717406, compound

Product 1

HCID 131717405HCID 131717405, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

A solution of Example 19 in methanol was treated with sodium borohydride at room temperature in the usual manner. This product was converted to the hydrochloride salt and crystallized from methanol-ether, m.p. 213°-215° (dec.).

Workup

  1. customcrystallized from methanol-ether, m.p. 213°-215° (dec.)

Sources & evidence

ORD record
ord-47770dff7e1445b589fab6b2c3e49be3
Source dataset
uspto-grants-1992_05
Patent number
US05116851

Reaction notes

Loading…