HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetic Anhydride → 2,6-dimethyl-4H-3,1-benzoxazin-4-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetic Anhydride | HCID 7918 | — |
| Reactant | 2-Amino-5-methylbenzoic acid | HCID 76255 | — |
| Product | 2,6-dimethyl-4H-3,1-benzoxazin-4-one | HCID 2796528 | — |
Reaction Steps
45.5 g (0.3 mol) of 5-Methylanthranilic acid are refluxed together with 130 g of acetic anhydride for 3 hours. After the solvent has been evaporated in vacuo, the residue is dissolved in 200 ml of dichloromethane, and the solution is filtered through silica gel. The concentrated filtrate is induced to crystallise with isopropyl ether.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05116971 |
| Source dataset | uspto-grants-1992_05 |
| ORD ID | ord-870075bdc07e436cbec7a3fd48b81d16 |
| Source note | uspto-grants-1992_05 |