HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1197168Generated: October 25, 2026
Carbon Dioxide → 4,5-dichloro-1H-imidazole-2-carboxylic Acid
https://huagongshe.com/reaction/1197168
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Carbon Dioxide | HCID 280 | — |
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | 4,5-Dichloroimidazole | HCID 140018 | — |
| Solvent | Water | HCID 962 | — |
| Product | 4,5-dichloro-1H-imidazole-2-carboxylic Acid | HCID 10976102 | 75.1% |
Reaction Steps
A mixture of 137 g (1 mol) of 4,5-dichloroimidazole, 414 g (3 mol) of K2CO3 and 1,000 ml of carbon dioxide was stirred in an autoclave at 200° C. under autogenous pressure for 10 hours. The solid output was pulverized, suspended in 2 1 of water and brought to pH 3-4 with concentrated hydrochloric acid while being cooled with ice. The resulting precipitate was filtered off and recrystallized from water to give 136 g (75%) of 4,5-dichloroimidazole-2-carboxylic acid (Compound No. 1); mp. 240° C. (dec.).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US05117004 |
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| Source dataset | uspto-grants-1992_05 |
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| ORD ID | ord-0888c105870f4432ae7118bbb6904123 |
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| Source note | uspto-grants-1992_05 |
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