Potassium Cyanide → HCID 19897885, compound

Participants

Reaction Steps

A mixture of 5.39 g of 4-chloromethyl-5,8-dimethyl-9-p-toluenesulfonylcarbazole obtained in Example 1(3), 1.82 g of potassium cyanide and 1.79 g of 18-crown-6 in 80 ml of acetonitrile was stirred at room temperature overnight. The reaction solution was poured into ice water and extracted with ethyl acetate, and the organic layer was washed, in turn, with a saturated aqueous sodium bicarbonate solution and a saturated aqueous sodium chlorided solution and dried over anhydrous magnesium sulfate. Evaporation of the solvent gave 5.21 g of 4-cyanomethyl-5,8-dimethyl-9-p-toluenesulfonylcarbazole.

Provenance & Evidence