HuagongsheHuagongshe Chemistry Print Report · For research reference only
2,5-Dimethoxytetrahydrofuran → Methyl 9H-carbazole-4-carboxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2,5-Dimethoxytetrahydrofuran | HCID 79098 | — |
| Reactant | p-Toluenesulfonic acid monohydrate | HCID 521998 | — |
| Reactant | methyl 1H-indole-4-carboxylate | HCID 2733668 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | Methyl 9H-carbazole-4-carboxylate | HCID 19897888 | 13.5% |
Reaction Steps
A mixture of 52.56 g of methyl indole-4-carboxylate, 51.55 g of 2,5-dimethoxytetrahydrofuran and 28.53 g of p-toluenesulfonic acid monohydrate in 300 ml of methanol was refluxed for 10 hours. Then, following a treatment similar to that of Example 1(1), there was obtained 9.14 g of methyl carbazole-4-carboxylate.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05116995 |
| Source dataset | uspto-grants-1992_05 |
| ORD ID | ord-47f4add07be140218692b7213a697950 |
| Source note | uspto-grants-1992_05 |