HCID 22850585, compound → HCID 54534523, compound

HRID 1197389Notes

Reaction equation

HRID 1197389 reaction equation
[CH2:1]([C:11]1[CH:12]=[N:13][C:14]([C:17]2[CH:22]=[CH:21][C:20]([O:23][CH2:24][CH2:25][C@@H:26]([F:31])[CH2:27][CH2:28][CH2:29][CH3:30])=[CH:19][CH:18]=2)=[N:15][CH:16]=1)[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH3:10].[CH2:32](C1C=NC(C2C=CC(O)=CC=2)=NC=1)[CH2:33]CCCCCCCCCC.CS(OCC[C@H](F)CCCC)(=O)=O>>[CH2:1]([C:11]1[CH:16]=[N:15][C:14]([C:17]2[CH:22]=[CH:21][C:20]([O:23][CH2:24][CH2:25][C@H:26]([F:31])[CH2:27][CH2:28][CH2:29][CH3:30])=[CH:19][CH:18]=2)=[N:13][CH:12]=1)[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:32][CH3:33]

Participants

4

Reactant 3

HCID 22850585HCID 22850585, compoundHCID 54434508(S)-5-Decyl-2-[4-(3-fluoroheptyloxy)phenyl]pyrimidineHCID 1360357064-(5-Dodecyl-2-pyrimidinyl)phenol

Product 1

HCID 54534523HCID 54534523, compoundYield 78.4%

Procedure

The titled compound was synthesized in a yield of 78.4% in the same manner as for the compound of Example 4, except for using 5-n-dodecyl-2-(4-hydroxyphenyl)pyrimidine and (R)-3-fluoroheptyl methanesulfonate.

Sources & evidence

ORD record
ord-94e530704a824078a97a01de76d58dce
Source dataset
uspto-grants-1994_01
Patent number
US05275756

Reaction notes

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