2-Aminothiophenol → HCID 19106821, compound

Participants

Reaction Conditions

Reaction Steps

The compound, 2-aminothiophenol, (12.5 g) was added to a solution of sodium hydroxide (4.5 g) in ethanol (100 ml) keeping the temperature less than 30° C. Then 1-bromo-2phenyl-2-propene (21 g) was added and the mixture was stirred at 60° C. for 3 h. The precipitated solid was filtered and washed with ethanol. The solvent was removed and the residue was chromatographed on silica gel with hexanes/ethyl acetate (7:1) to yield the title compound (14.5 g). As an oil.

Provenance & Evidence