HCID 88461698, compound → HCID 57055805, compound

Participants

Reaction Steps

Prepared from (-)-(S)-2-(2,3,4,5, 6-pentafluorobenzyloxyamino)-N-methyl-1-(3-pyridyl)cyclohexanecarbothioamide (0.49 g) as described in Example 1. The crude product was subjected to flash chromatography on silica gel eluting with chloroform/methanol: 98.5/1.5 to give (1S,2R)-2-(2,3,4,5,6-pentafluoro-benzyloxyamino)-N-methyl-1-(3-pyridyl)cyclohexanecarbothioamide, a yellow solid (0.34 g, 69%), m.p. 57°-60°. Found: C, 53.7; H, 4.37; N, 9.5%; C20H20F5N3OS requires C, 53.9; H, 4.53; N, 9.43%.

Provenance & Evidence