HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetoacetic Acid → HCID 57026684, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetoacetic Acid | HCID 96 | — |
| Reactant | Acetic Anhydride | HCID 7918 | — |
| Reactant | Benzene, (cyclohexylmethyl)- | HCID 20444 | — |
| Solvent | Pyridine | HCID 1049 | — |
| Product | HCID 57026684 | HCID 57026684 | — |
Reaction Steps
The title compound is prepared by the microbial oxidation of cyclohexylmethylbenzene (W. Korte et al. J. Org. Chem. 39, 1168-70 (1974)) by Pseudomonas putida 39D using the method of T. Hudlicky et al. J. Am. Chem. Soc. 110, 4735-41 (1988) and D. Gibson et al. Biochemistry, 9, 1626-30 (1970) followed by protection as the diacetate using acetic anhydride in pyridine.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05275950 |
| Source dataset | uspto-grants-1994_01 |
| ORD ID | ord-62a2d5ce38274989841c78679a1a9563 |
| Source note | uspto-grants-1994_01 |