HuagongsheHuagongshe Chemistry Print Report · For research reference only
1,4-Dioxane → Cyclopentanone, 2-[(2-bromophenyl)methyl]-
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1,4-Dioxane | HCID 31275 | — |
| Reactant | 2-Bromobenzyl bromide | HCID 76965 | — |
| Reactant | Pyrrolidine, 1-(1-cyclopenten-1-yl)- | HCID 81570 | — |
| Product | Cyclopentanone, 2-[(2-bromophenyl)methyl]- | HCID 10354892 | 45% |
Reaction Steps
In a manner similar to that described in Example 82, 1-pyrrolidino-1-cyclopentene (15.1 g, 0.11 mole) in dioxane (100 ml) was treated with 2-bromobenzyl bromide (30.0 g, 0.12 mol) to give the title compound as a clear oil (12.5 g, 45%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05276053 |
| Source dataset | uspto-grants-1994_01 |
| ORD ID | ord-fc2bcbf414cb447a8d41b3b9d447be96 |
| Source note | uspto-grants-1994_01 |