Bis(trifluoroacetoxy)iodobenzene → HCID 54375431, compound

HRID 1197569Notes

Reaction equation

HRID 1197569 reaction equation
NC([CH:4]1[CH2:9][CH2:8][CH:7]([N:10]2[CH2:14][CH2:13][N:12]([C:15]3[CH:20]=[CH:19][C:18]([CH2:21][CH2:22][CH2:23][C:24]([O:26][CH3:27])=[O:25])=[CH:17][CH:16]=3)[C:11]2=[O:28])[CH2:6][CH2:5]1)=O.FC(F)(F)C(OI(C1C=CC=CC=1)OC(=O)C(F)(F)F)=O.C(#[N:52])C.O>>[NH2:52][CH:4]1[CH2:5][CH2:6][CH:7]([N:10]2[CH2:14][CH2:13][N:12]([C:15]3[CH:20]=[CH:19][C:18]([CH2:21][CH2:22][CH2:23][C:24]([O:26][CH3:27])=[O:25])=[CH:17][CH:16]=3)[C:11]2=[O:28])[CH2:8][CH2:9]1

Participants

4

Reactant 3

HCID 102317Bis(trifluoroacetoxy)iodobenzeneHCID 18373917Acetonitrile--water (1/1)HCID 22098845HCID 22098845, compound

Product 1

HCID 54375431HCID 54375431, compound

Procedure

Prepared from 1-(4-aminocarbonyl-cyclohexyl)-3-[4-(3-methoxycarbonyl-propyl)-phenyl]-imidazolidin-2-one by treating with [bis-(trifluoroacetoxy)iodo]benzene in acetonitrile/water at ambient temperature.

Sources & evidence

ORD record
ord-cd75ae7f146e44a8892287900eb4c2a5
Source dataset
uspto-grants-1994_01
Patent number
US05276049

Reaction notes

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