5-(4'-(Bromomethyl)(1,1'-biphenyl)-2-yl)-1-trityl-1H-tetraazole → HCID 178440186, compound

HRID 1197595Notes

Reaction equation

HRID 1197595 reaction equation
[C:1]([C:3]1[NH:7][C:6]([CH2:8][CH2:9][CH3:10])=[N:5][C:4]=1[N:11]1[C:15]([Cl:16])=[CH:14][CH:13]=[C:12]1[Cl:17])#[N:2].C1(C(C2C=CC=CC=2)(C2C=CC=CC=2)[N:25]2[C:29]([C:30]3[CH:35]=[CH:34][CH:33]=[CH:32][C:31]=3[C:36]3[CH:41]=[CH:40][C:39]([CH2:42]Br)=[CH:38][CH:37]=3)=[N:28][N:27]=[N:26]2)C=CC=CC=1>>[C:1]([C:3]1[N:7]([CH2:42][C:39]2[CH:40]=[CH:41][C:36]([C:31]3[CH:32]=[CH:33][CH:34]=[CH:35][C:30]=3[C:29]3[NH:25][N:26]=[N:27][N:28]=3)=[CH:37][CH:38]=2)[C:6]([CH2:8][CH2:9][CH3:10])=[N:5][C:4]=1[N:11]1[C:15]([Cl:16])=[CH:14][CH:13]=[C:12]1[Cl:17])#[N:2]

Participants

3

Reactant 2

HCID 100534615-(4'-(Bromomethyl)(1,1'-biphenyl)-2-yl)-1-trityl-1H-tetraazoleHCID 19106942HCID 19106942, compound

Product 1

HCID 178440186HCID 178440186, compound

Procedure

Using the procedure from Example 13, 5-cyano-4-(2,5-dichloro-1H-pyrrol-1-yl)-2-propylimidazole (Example 30) and N-triphenylmethyl-5-[4'-(bromomethyl)biphenyl-2-yl]tetrazole (Example 12) are reacted and deprotected to give the title compound.

Workup

  1. customare reacted

Sources & evidence

ORD record
ord-72b014cd16ac4a7c9303be97904aebe2
Source dataset
uspto-grants-1994_01
Patent number
US05276048

Reaction notes

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