HCID 19107610, compound → Benzenesulfonamide

HRID 1197657Notes

Reaction equation

HRID 1197657 reaction equation
C1(C([NH:15][S:16]([C:19]2[CH:24]=[CH:23][C:22](CBr)=[CH:21][CH:20]=2)(=[O:18])=[O:17])CC2C=CC=CC=2)C=CC=CC=1>C1COCC1.CN(C=O)C>[C:19]1([S:16]([NH2:15])(=[O:18])=[O:17])[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=1

Participants

3

Reactant 1

HCID 19107610HCID 19107610, compound

Product 1

HCID 7370BenzenesulfonamideYield 1%

Reagents, catalysts & solvents 1

HCID 21974620tetrahydrofuran N,N-dimethylformamideSolvent

Procedure

N-Ethyl-N-(S)-1-isobutyl-2-ethoxyethyl 3-chloro-4-(3H-2-methylimidazo [4,5-c]pyridylmethyl)benzenesulphonamide and (B) N-ethyl-N-(S)-1-isobutyl-2-ethoxyethyl 3-chloro-4-(1 H-2-methylimidazo [4,5-c]pyridylmethyl)benzenesulphonamide were prepared by the method of Example 17 utilizing N-Ethyl-N-(S)-1-isobutyl-2-ethoxyethyl 3-chloro-4-bromo-methylbenzenesulphonamide in lieu of N-1,2-diphenylethyl 4-bromomethylbenzenesulphonamide and 3:1 THF/DMF as solvent.

Sources & evidence

ORD record
ord-dfb456c0ad3e4685b57aa9839c9efb3c
Source dataset
uspto-grants-1994_01
Patent number
US05276153

Reaction notes

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