HuagongsheHuagongshe Chemistry Print Report · For research reference only
Phenylpyruvic acid → HCID 19104969, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Phenylpyruvic acid | HCID 997 | — |
| Reactant | β,β-Diethoxy-3-pyridineethanamine | HCID 10987537 | — |
| Product | HCID 19104969 | HCID 19104969 | — |
Reaction Steps
In a manner analogous to Example 1, by condensing 3-(2-amino-1,1-diethoxyethyl)pyridine with phenylpyruvic acid there is obtained N-[2,2-diethoxy-2-(3-pyridyl)ethyl]-3-phenylpyruvamide as an amorphous, yellow solid. Subsequent acidic hydrolysis to 3-phenyl-N-[[(3-pyridyl)carbonyl]methyl]pyruvamide and ring closure gives 3-benzyl-5-(3-pyridyl)-2(1H)-pyrazinone as a solid, melting point 188°-190° (from ethyl acetate).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05278161 |
| Source dataset | uspto-grants-1994_01 |
| ORD ID | ord-f342c34c7a404e9ba6895a5898b576f6 |
| Source note | uspto-grants-1994_01 |