4-Chlorophenyl Isocyanate → HCID 10071500, compound

Participants

Reaction Steps

To a solution of 3-amino-6,7-dimethyl-4-(2-methylphenyl)-2H-1-benzopyran-2- one (279 mg) in tetrahydrofuran (4 ml) was added 4-chlorophenylisocyanate (184 mg). The mixture was stirred for 3 days at room temperature and distilled to remove the solvent. Ethyl ether was added to the residue to obtain crystals of N-(4-chlorophenyl)-N'-[6,7-dimethyl-4-(2-methylphenyl)-2-oxo-2-H-1-benzopyran-3-yl] urea (382 mg, 88.2%). Recrystallization from acetone gave colorless needles.

Provenance & Evidence