3-(Trifluoromethyl)phenyl isocyanate → HCID 54383764, compound

Participants

Reaction Steps

A mixture of 3-amino-6-chloro-7-methyl-4-(2-methylphenyl)-2H-benzopyran-2- one (297 mg), 3-trifluoromethylphenylisocyanate (374 mg) and benzene (4 ml) was refluxed for 2 hours and then distilled to remove the solvent. The residue was crystallized from ethyl ether. The resulting crystals were recrystallized from ethanol to obtain colorless needles of N-[6-chloro-7-methyl-4-(2-methylphenyl)-2-oxo- 2H-1-benzopyran-3-yl]-N'-(3-trifluoromethylphenyl) urea.

Provenance & Evidence