Hydrochloric Acid → HCID 19105284, compound

Participants

Reaction Conditions

Reaction Steps

A mixture of ethyl 6-chloro-4-(3,5-di-tert-butyl-4-hydroxyphenyl)-2-oxo-2H-1-benzopyran-3-carboxylate (2.0 g), 2N NaOH (11 ml) and ethanol (20 ml) was heated at 70° C. for 10 minutes. Then, the mixture was made acid with 2N HCl and extracted with ethyl acetate. The extract was washed with water and dried (MgSO4), and then, the solvent was removed to obtain 6-chloro-4-(3,5-di-tert-butyl-4-hydroxyphenyl)-2-oxo-2H-1-benzopyran-3-carboxylic acid as powders (1.3 g, 69.1%).

Provenance & Evidence