関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | 4-Chlorostyrene | HCID 14085 | — |
| 反応物 | Magnesium | HCID 5462224 | — |
| 反応物 | Chloro(dimethyl)[(propan-2-yl)oxy]silane | HCID 13033739 | — |
| 反応物 | HCID 178436504 | HCID 178436504 | — |
| 溶媒 | Tetrahydrofuran | HCID 8028 | — |
| 生成物 | 1-[Dimethyl(1-methylethoxy)silyl]-4-ethenylbenzene | HCID 18961613 | 45% |
反応手順
A solution of isopropoxydimethylchlorosilane (15.2 g, 100 mmole) in dry THF (50 mL) was added dropwise over a 1 hour period to a solution of (4-vinylphenyl)magnesium chloride, prepared from 4-vinylphenyl chloride (13.85 g, 100 mmole) and magnesium (3.0 g, 125 mmole) in dry 100 mL THF. The temperature was maintained at 10° C. during the addition. The reaction mixture was stirred at room temperature for over 18 hours. The desired product distilling at 45°-49° C./0.2 mm was obtained in 45% yield.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US05278244 |
|---|
| 出典データセット | uspto-grants-1994_01 |
|---|
| ORD ID | ord-03f27159cd4f48c8bc89eff936c386cd |
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| 出典メモ | uspto-grants-1994_01 |
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