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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1198097Generated: October 27, 2026

L-Phenylalanine, methyl ester → N-(Benzyloxycarbonyl)-L-aspartyl-L-phenylalanine methyl ester

https://huagongshe.com/reaction/1198097

Reaction equation

Participants

RoleNameHCIDCharge
ReactantL-Phenylalanine, methyl esterHCID 736234—
ReactantN-(Benzyloxycarbonyl)aspartic acidHCID 2723942—
ProductN-(Benzyloxycarbonyl)-L-aspartyl-L-phenylalanine methyl esterHCID 10159630—

Reaction Steps

condensing the N-benzyloxycarbonyl-L-aspartic acid with the L-phenylalanine methyl ester through the action of the papain at a temperature of between 25° C. and 49° C to yield N-benzyloxycarbonyl-α-L-aspartyl-L-phenylalanine methyl ester; and

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05279946
Source datasetuspto-grants-1994_01
ORD IDord-068d955b7d974649b222f44b08f1cac5
Source noteuspto-grants-1994_01