HuagongsheHuagongshe Chemistry Print Report · For research reference only
N-Methylaniline → 2-Chloro-4-(N-methylphenylamino)thieno[2,3-d]pyrimidine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | N-Methylaniline | HCID 7515 | — |
| Reactant | 2,4-Dichlorothieno[2,3-d]pyrimidine | HCID 12217324 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 2-Chloro-4-(N-methylphenylamino)thieno[2,3-d]pyrimidine | HCID 10356057 | — |
Reaction Steps
2,4-Dichlorothieno[2,3-d]pyrimidine (4.5 g, 0.022 mol) and N-methylaniline (4.7 g, 0.044 mol) in ethanol (50 ml) were stirred at room temperature for 72 hours. The solid obtained was collected by filtration, washed with ethanol and dried, 5.15 g. Recrystallization from ethyl acetate gave the title compound, m.p. 167°-168°.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05280026 |
| Source dataset | uspto-grants-1994_01 |
| ORD ID | ord-5033a70d127f425d83e1f8f3beeda801 |
| Source note | uspto-grants-1994_01 |