HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrazine hydrate (1:1) → 4-Phenoxybutan-1-amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrazine hydrate (1:1) | HCID 24654 | — |
| Reactant | 2-(4-Phenoxybutyl)-1H-isoindole-1,3(2H)-dione | HCID 16637597 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 4-Phenoxybutan-1-amine | HCID 116240 | 96.2% |
Reaction Steps
A mixture of N-(4-phenoxybutyl)phthalimide (7.8 g), hydrazine hydrate (7 ml) and ethanol (150 ml) was stirred for one hour under reflux. Crystalline precipitate was filtered off, then the filtrate was concentrated under reduced pressure to give 4-phenoxybutylamine (4.2 g, 95%) as an oily product.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05280022 |
| Source dataset | uspto-grants-1994_01 |
| ORD ID | ord-43de905befef4fd6a66a6a7f25f015a2 |
| Source note | uspto-grants-1994_01 |