HCID 19104007, compound → HCID 19103985, compound

HRID 1198133Notes

Reaction equation

HRID 1198133 reaction equation
[Cl:1][C:2]1[C:3]([NH:11][CH:12]([C:14]2[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=2)[CH3:13])=[N:4][CH:5]=[N:6][C:7]=1[CH:8](Cl)[CH3:9].[Na].[CH3:21][SH:22]>CO>[Cl:1][C:2]1[C:3]([NH:11][CH:12]([C:14]2[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=2)[CH3:13])=[N:4][CH:5]=[N:6][C:7]=1[CH:8]([S:22][CH3:21])[CH3:9]

Participants

4

Reactant 2

HCID 19104007HCID 19104007, compoundHCID 45051789Methylmercaptan sodium

Product 1

HCID 19103985HCID 19103985, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

In 30 ml of methanol was dissolved 1.20 g of 5-chloro-6-(1-chloroethyl)-4-(1-phenylethylamino)pyrimidine, and to the mixture was added 2.89 g of a methanethiol sodium salt 15% aqueous solution. The mixture was stirred at room temperature for 3 hours.

Sources & evidence

ORD record
ord-dc8fa406f20c4123ae6d784e18b3fda5
Source dataset
uspto-grants-1994_01
Patent number
US05280025

Reaction notes

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