HuagongsheHuagongshe Chemistry Print Report · For research reference only
1,1'-Carbonyldiimidazole → N-(tetrahydro-1H-pyrrolizin-7a(5H)-ylmethyl)imidazo[1,2-a]pyridine-2-carboxamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1,1'-Carbonyldiimidazole | HCID 68263 | — |
| Reactant | Imidazo[1,2-a]pyridine-2-carboxylic acid | HCID 2062168 | — |
| Reactant | (Hexahydro-1H-pyrrolizin-7A-YL)methanamine | HCID 10654304 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | N-(tetrahydro-1H-pyrrolizin-7a(5H)-ylmethyl)imidazo[1,2-a]pyridine-2-carboxamide | HCID 9817290 | — |
Reaction Steps
Imidazo[1,2-a]pyridine-2-carboxylic acid is reacted with carbonyldiimidazole in dimethylformamide and subsequently with 7a-aminomethylhexahydro-1H-pyrrolizine to afford the title compound upon workup.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05280029 |
| Source dataset | uspto-grants-1994_01 |
| ORD ID | ord-f298219b4f774da3b5bdaf5c8f42887d |
| Source note | uspto-grants-1994_01 |