Ethanol → HCID 7009563, compound

Participants

Reaction Steps

Triethylamine (206 g) and 4-methoxybenzyl chloride (89 g) were added in turn to a solution of cysteine hydrochloride (107 g) in a 2:1 v/v mixture of ethanol and water (1000 ml). The mixture was stirred at laboratory temperature for 16 hours. The mixture was filtered to give S-(4-methoxybenzyl)cysteine (107.4 g). The filtrate was stored -10° C. for 48 hours and a second crop (22.3 g) of the cysteine derivative was obtained.

Provenance & Evidence