Diethyl Malonate → Diethyl 2-[(4-octylphenyl)methylene]propanedioate

HRID 1198216Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1198216
[C:1]([O:9][CH2:10][CH3:11])(=[O:8])[CH2:2][C:3]([O:5][CH2:6][CH3:7])=[O:4].[CH2:12]([C:20]1[CH:27]=[CH:26][C:23]([CH:24]=O)=[CH:22][CH:21]=1)[CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH3:19]>N1CCCCC1>[CH2:12]([C:20]1[CH:27]=[CH:26][C:23]([CH:24]=[C:2]([C:3]([O:5][CH2:6][CH3:7])=[O:4])[C:1]([O:9][CH2:10][CH3:11])=[O:8])=[CH:22][CH:21]=1)[CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH3:19]

Komponenten

4

Edukt 2

HCID 7761Diethyl MalonateHCID 2734685Benzaldehyde, 4-octyl-

Produkt 1

HCID 19104284Diethyl 2-[(4-octylphenyl)methylene]propanedioate

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 8082PiperidineKatalysator

Reaktionsbedingungen

Temperatur
100 °C

Versuchsvorschrift

Diethyl malonate (1.76g, 0.011 moles), paraoctylbenzaldehyde (2.4g, 0.011 moles) and piperidine (5 drops) were heated to 98° C. for 2.5 hrs. and 45° C. for 16 hrs. The solution was heated to 100° C. for 64 hrs. The title compound was purified by silica gel chromatography. The structure assignment was supported by NMR, infrared and uv spectra and elemental analysis (360.5).

Aufarbeitung

  1. customThe title compound was purified by silica gel chromatography

Quellen und Nachweise

ORD-Eintrag
ord-5af11e0ea1b04ddd8ec610c4fed85d0d
Quelldatensatz
uspto-grants-1994_01
Patentnummer
US05280047

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