Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Benzaldehyde | HCID 240 | — |
| Reactant | Methyl vinyl ketone | HCID 6570 | — |
| Reactant | Triethylamine | HCID 8471 | — |
| Catalyst | 3-Benzyl-5-(2-hydroxyethyl)-4-methylthiazolium chloride | HCID 2833352 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 1-Phenyl-1,4-pentanedione | HCID 136371 | — |
Reaction Steps
A mixture of 8.1 g (0.03 mol) 3-benzyl-5-(2-hydroxyethyl)-4-methyl-1,3-thiazolium chloride, 180 ml triethylamine, 150 ml ethanol, 21 g of 1-butene-3-one (0.3 mol) and 30.7 g of benzaldehyde (0.29 mol) was gently stirred at 80° C. for 16 hours. Volatile components were removed by evaporation. The 1-phenyl-1,4-pentanedione thus formed was recovered by extraction and subsequent vacuum distillation.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US05279999 |
|---|
| Source dataset | uspto-grants-1994_01 |
|---|
| ORD ID | ord-90cbba4aab5545cd868be8f5a9867dbe |
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| Source note | uspto-grants-1994_01 |
|---|
