HuagongsheHuagongshe Chemistry Print Report · For research reference only
Toluene → (4-Octyloxy-2,3-difluorophenyl)-4-propylbenzylideneamine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Toluene | HCID 1140 | — |
| Reactant | p-Toluenesulfonic acid | HCID 6101 | — |
| Reactant | 4-Propylbenzaldehyde | HCID 120047 | — |
| Reactant | HCID 19103699 | HCID 19103699 | — |
| Solvent | Water | HCID 962 | — |
| Product | (4-Octyloxy-2,3-difluorophenyl)-4-propylbenzylideneamine | HCID 53700525 | — |
Reaction Steps
A mixture of 0.1 mol of 4-octyloxy-2,3-difluoroaniline (prepared from the corresponding amide by a Hoffmann rearrangement), 0.1 mol of 0.1 mol of 4-propylbenzaldehyde, 0.01 mol of p-toluenesulfonic acid and 200 ml of toluene is heated at the boiling point for 2 hours using a water separator. Customary working up gives (4 -octyloxy-2,3-difluorophenyl)-4-propylbenzylideneamine.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05279764 |
| Source dataset | uspto-grants-1994_01 |
| ORD ID | ord-57591a8a019f4316908f5443038ffd6d |
| Source note | uspto-grants-1994_01 |