HuagongsheHuagongshe Chemistry Print Report · For research reference only
Cyclohexyl isothiocyanate → Hydrazinecarbothioamide, 2-(1-(2-pyridinyl)ethylidene)-
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Cyclohexyl isothiocyanate | HCID 14289 | — |
| Reactant | HCID 474761 | HCID 474761 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | Hydrazinecarbothioamide, 2-(1-(2-pyridinyl)ethylidene)- | HCID 2732427 | 46% |
Reaction Steps
A solution of 6.76 g (0.05 mol) of 2-acetylpyridine hydrazone in 10 ml of MeOH was treated with 7.2 g (0.05 mol) of cyclohexyl isothiocyanate and the solution was heated at reflux for 3 hours. The solution was chilled, and the crystals which formed were collected. Recrystallization of the product from 150 ml of MeOH afforded 6.40 9 (46%) of white needles of 2-acetylpyridine 4-cyclohexyl-3-thiosemicarbazone, mp 155° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05281597 |
| Source dataset | uspto-grants-1994_01 |
| ORD ID | ord-ba56af65238d4592aef5b948ea14edf2 |
| Source note | uspto-grants-1994_01 |