HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl 3-[2(E)-(quinolin-2-yl)ethenyl]benzoate → 3-[2(E)-(Quinolin-2-yl)ethenyl]benzyl alcohol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl 3-[2(E)-(quinolin-2-yl)ethenyl]benzoate | HCID 19959111 | — |
| Reactant | Aluminium lithium hydride | HCID 21226445 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Solvent | Sodium Hydroxide | HCID 14798 | — |
| Product | 3-[2(E)-(Quinolin-2-yl)ethenyl]benzyl alcohol | HCID 70110002 | — |
Reaction Steps
Solid lithium aluminium hydride (0.25 g) was added in portions to a stirred solution of methyl 3-[2(E)-(quinolin-2-yl)ethenyl]benzoate (2.1 g, 7.3 mmol) in tetrahydrofuran (50 ml). The mixture was stirred for 30 minutes, diluted with sodium hydroxide solution and extracted with ethyl acetate. The extract was dried and evaporated and the residue was chromatographed on silica in ethyl acetate-hexane (1:1).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05281593 |
| Source dataset | uspto-grants-1994_01 |
| ORD ID | ord-8c1737dd31744314bfac3358eb33d22e |
| Source note | uspto-grants-1994_01 |