Ammonium Chloride → HCID 15054015, compound

Participants

Reaction Conditions

Reaction Steps

M Vinyl magnesium bromide solution in tetrahydrofuran (80 ml) was added to a stirred solution of 2-benzyloxy-5-chloronitrobenzene (5.28 g, 20 mmol) in tetrahydrofuran (160 ml) at -40° C. The mixture was stirred for 2 hours at -40° C. then poured onto saturated ammonium chloride solution (500 ml) and extracted with ether. The extract was dried and evaporated and the residue was chromatographed on silica in ethyl acetate-hexane (1:8) to give a yellow oil.

Provenance & Evidence